Our skin is home to a diverse community of microorganisms known as the skin microbiome. This complex ecosystem plays a crucial role in maintaining skin health and protecting against various dermatological conditions.
This microbial community helps to:
- Defend Against Pathogens: The microbiome acts as a first line of defense against harmful pathogens by competing for resources and producing substances that can inhibit or kill potential invaders. This helps prevent infections and skin disorders like acne, eczema, or even more severe conditions like psoriasis.
- Strengthen the Immune System: The skin microbiome interacts closely with the immune system, teaching it to differentiate between harmful invaders and harmless substances. This immune “education” helps to prevent overactive immune responses, such as allergic reactions or autoimmune conditions.
- Support Skin Barrier Function: The microbiome also contributes to maintaining the skin’s natural barrier, which is crucial for preventing dehydration and shielding against environmental stressors like pollutants, UV radiation, and allergens.1
In return, the skin provides a stable environment for these microorganisms, offering nutrients like sebum (oil) and sweat to support their growth. This mutual relationship is essential for skin health, and disruptions in the microbiome can lead to skin conditions.
The skin microbiome forms in infancy and evolves over time, influenced by genetics, environmental factors, and lifestyle choices. When imbalances, known as dysbiosis, occur, skin conditions like infections, allergies, or disorders can arise.

Environmental Factors Affecting the Skin Biome:
- UV Radiation: Sun exposure and tanning bed use can alter the skin’s microbial community.
- Pollution: Environmental pollutants can disrupt the microbiome.
- Climate: Changes in temperature and humidity can also impact the skin’s microbial balance, making the skin more prone to dryness or irritation.
Lifestyle Factors Affecting the Skin Biome:
- Diet: What we eat can have a direct impact on our skin. Diets high in fats and sugars can disrupt the microbial balance of the skin, while a diet rich in antioxidants, vitamins, and healthy fats can promote a thriving microbiome.
- Skincare Routine: Harsh skincare products, such as soaps with strong detergents or products that alter the skin’s natural pH, can disturb the microbiome. Overuse of such products can strip away beneficial bacteria and create an environment that favours harmful microbes.
- Skin Hygiene: Poor hygiene routines, including infrequent washing or over-washing, can alter the balance of skin microbes, potentially leading to breakouts or irritation.
- Occupation: Certain professions expose individuals to environmental stressors like chemicals or physical irritants, which can impact the skin’s microbiome.
- Antibiotic Usage: While antibiotics are essential for treating infections, overuse or misuse can disrupt the skin’s microbial community. They can kill both harmful and beneficial bacteria, leading to imbalances and potentially increasing the risk of skin conditions.

Natural Processes Affecting the Skin Biome:
- Skin Aging: As we age, the skin undergoes several changes, including reduced sebum (oil) production, thinning of the skin, and shifts in pH. These changes can influence the composition of the skin microbiome, making the skin more susceptible to dryness, irritation, and microbial imbalances.
- Hormonal Changes: Hormonal fluctuations, such as those experienced during puberty or menopause, can affect the production of sebum and influence the skin microbiome. Increased sebum production during puberty, for instance, can contribute to acne by altering the microbial balance.
- Genetics: Genetic factors also play a significant role in the skin microbiome. For example, individuals with certain genetic predispositions, like a deficiency in filaggrin (a protein important for skin barrier function), may be more susceptible to skin conditions like eczema or dermatitis due to an altered microbiome.
The skin microbiome is a dynamic and essential component of overall skin health. Maintaining a balanced microbiome is crucial for protecting the skin against pathogens, supporting immune function, and preserving the skin’s natural barrier. Imbalances in the skin microbiome have been associated with many disorders such as atopic dermatitis (eczema), seborrheic dermatitis, psoriasis, acne and rosacea.
While research into the skin microbiome and its potential for modification shows great promise, it remains in its early stages. Continued studies are crucial to fully understand the intricate interactions within the microbiome and how these can be harnessed to prevent and treat dermatological conditions. By gaining a deeper understanding of the factors that influence the microbiome, we can take proactive steps to nurture and protect this vital ecosystem, fostering healthier, more resilient skin.
If you’re looking to improve your skin health, consider booking an appointment at Nutrichem Clinic. Our expert team can help you understand your skin’s needs and create a personalized plan to restore balance. Book today for a healthier, more resilient complexion!
References
Haykal D, Cartier H, Dréno B. Dermatological Health in the Light of Skin Microbiome Evolution. Journal of Cosmetic Dermatology. 2024;23(12):3836-3846.
Grice EA, Segre JA. The skin microbiome. Nature reviews Microbiology. 2011;9(4):244.
Yang Y, Qu L, Mijakovic I, Wei Y. Advances in the human skin microbiota and its roles in cutaneous diseases. Microbial Cell Factories. 2022;21(1):1-14.